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Viagra may reverse enlarged-heart damage
A recent study on mice concluded [January 2005] that Viagra successfully treated enlargement of the heart
Later this year will be a trial involving men.
Main conclusions of study were that Viagra:
- stopps further growth of the heart muscle,
- actually reverses the growth and damage that had already taken place,
- might block the "bad" heart hypertrophy.
Viagra works in human body by inhibiting an enzyme called PDE5A.
Inhibiting the action of PDE5A in the penis, Viagra relaxes the smooth muscle, allowing the blood to flow.
In the heart muscle, producing a direct relaxation response, it helps break down a cyclic molecule that
acts to curb stresses and overgrowth in the heart.
Dr. Hunter Champion, assistant professor of medicine at Johns Hopkins University School of Medicine considers
the result very impressive because it works on more than just one experiment. He thinks that heart disease is
a important problem in the United States. The best think in his opinion is the fact that Viagra is a safe drug
for future experiences in the second part of 2005.
This important qualifying comes from the existence of more than 20 millions of prescribed scripts in United States.
The study co-author, Dr. Richard Stein, a national spokesman for the American Heart Association says that the
conclusion of study is very important. In his opinion, what was good for mice, will be good for humans as well.
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