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Levitra improves satisfaction among men with premature ejaculation
Presenting the findings from a small pilot study here May 23rd at the American Urological Association (AUA) Annual Meeting.
Frank Sommer, MD, professor of urology at the University of Cologne, Germany, said that
his team may report that treatment of premature ejaculation -- the most common male sexual dysfunction -- with the
antidepressant sertraline (Zoloft) improves the condition, but treatment with the oral anti-impotence agent Levitra
succeeds even better.
During in his presentation on behalf of the German Men's Health Study Group, professor Sommer said
"There is a potential usefulness of vardenafil as a promising line of therapy in premature ejaculation."
Presenting the pilot study, Sommer said he and colleagues enrolled 34 men and randomized them to receive either
50 mg of sertraline 4 hours before intercourse or 10 mg of Levitra about 30 minutes before attempted intercourse.
The men had to have self-rated premature ejaculation scores of 4 or higher and intravaginal ejaculatory latency time
(IVELT) of less than 1.5 minutes.
After a 6 weeks period, the men were given a 1-week washout period before being crossed over to the alternate treatment.
The team made the evaluation for primary and secondary premature ejaculation, grading their ejaculation on a scale of 0 to 8,
with 0 meaning they never had premature ejaculation and 8 meaning premature ejaculation occurred almost every time they
had intercourse.
By the 6-week evaluation, the mean premature ejaculation score improved from 6.14 at baseline to 4.28 with sertraline
and to 3.2 with vardenafil -- almost a 50% improvement for vardenafil over baseline, Dr. Sommer noted.
While the results were encouraging, the team leader said, "The place of vardenafil in the therapy of premature ejaculation awaits larger patient samples and placebo-controlled studies to confirm these results."
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