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Vascular disease most common cause of male erectile dysfunction
Dr. Graham Jackson established a unique clinic in England dedicated to providing sexual advice to men with
cardiac disease and ED.
In the study, appearing in the July 2005 issue of The Journal of Sexual Medicine, Dr. Jackson wished to see
if stable coronary patients with ED could have their oral nitrates discontinued to allow for safe use of a PDE-5
inhibitor, such as Viagra, Levitra or Cialis.
For the first time in a large prospective study, that certain of his patients with erectile dysfunction (ED) and heart
problems can now safely use erection drugs that help up to 80% of men restore function and quality of life.
Dr G. Jackson conducted the largest scientific study of its kind, on 425 men with ED and cardiac disease.
More than half of the men on oral nitrates who were clinically stable with good ability to exercise had their
nitrates discontinued in the presence of continuing beta-blockade or calcium antagonist therapy and close
follow-up. Over 90% of the men no longer taking nitrates were treated with a PDE-5 inhibitor which was
effective in restoring sexual function in 85%. Importantly, there have been no adverse cardiac events in the group.
The Center for Disease Control and Prevention estimates that 1 in 12 (8%) or 22 million adults in the US
have heart disease. In the US, the prevalence rate for those who have angina pectoris is 17.5 per 1000 people.
Nitrate therapy is an absolute contraindication to the use of PDE-5 inhibitors
"If you are on nitrates, the best advice is to see your doctor," states Irwin Goldstein MD,
Editor-in-Chief of The Journal of Sexual Medicine
NOTE: The Information on this site is provided for information only,
and is not meant to substitute for the advice of your own physician or other medical professional.
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