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Living donor pancreas transplant successfully helps diabetes




Living donor pancreas transplant successfully helps in diabetes


According to early online edition of The Lancet on Monday 18 April 2005 a researcher team in Japan have successfully performed a living pancreatic islet transplantation.

The donor was a woman, 56 years old, healthy and not obese having a healthy glucose pattern and insulinogenic index.

The recipient was her daughter, 27 years old, with insulin-dependent diabetes developed at age 15. Initially, the young women has developed chronic pancreatitis at 4 years of age. The daughter had frequent hypoglycemic episodes of which she was unaware.

The mother was released 18 days after the transplantation, at which time her OGTT (oral glucose tolerance test ) results were very normal. The daughter became insulin independent on day 22, and has continued so for the 2 months since the operation. She was discharged on day 37 after the operation having excellent glycemic control and normal OGIT.

Dr. Matsumoto, the team leader said: "Our successful transplantation might have implications for the ongoing transition of the procedure, from clinical investigation to routine clinical care"

Compared with insulin therapy, the islet transplant has a greater likelihood of avoiding vascular and other complications of diabetes and could provide the patient with normal glycemic control . This therapy should be a new solution for severe diabetes, especially for patients developing frequent hypoglycemia.




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